I usually travel with the Sony super zoom DSC-HX1 but hated the shutter lag so I have put together a Nex-7 "system" mainly when I want to travel light.
I will chime in for some thoughts after a couple of short trips using just Nex-7, SEL18-200 and Zeiss Sel 24f1.8
1. Although much quicker than the HX1 but be aware of the limitation of the Contrast Base AF. Speed is OK but the main shortcoming is you have to use DMF to confirm whether the sharpest focused point is where you want it. For example, the camera might decide on some jewelry around the neck instead of the eye. Good thing the manual focus and peaking is VERY good so using non AF adapter and MF lenses like the STF is very easy.
2. No more in camera anti-shake so lens like the 18-200 with OSS is great but one has to go back to the inverse focal length "rule" for shutter speed with lenses like the 24mmZeiss (would that be 35mm equivalent so 1/35 sec?)
3. The hood design for lenses like the Zeiss 24mm and the 50mm is such that some protective filters with thick rim would block the fitting on of the hood.
4. Fat/long lens like the 18-200 would block the internal flash and the low light AF assisst light. The AF light is in body and not the same as the ones on FA58, 43 or other Sony/Minolta flashes.
5. The weight is pretty light even with the 18-200 so one can get away with light tripod or trek-pod.
6. I have small hands so I have only video my feet a few times by accident but larger hands beware.
7. Nex-7 and Zeiss 24mm SEL is somehow the best combo for food I have used so far.