I work with the basic options out of the 30 billion. Levels, adjustment on shadows, highlights and midtones (on a separate non destructive layer), curves and sharpening. If added value, a bit of color saturation. I try to stick to this workflow as much as I can as it speeds up the processing time.
By now I know exactly how far I can push the sliders in combination with the camera and lenses I use so that is pretty much the combination that you need to look for. Try to have a consistent input to output flow as well, I process exclusively in AdobeRGB. (Convert to sRGB for web upload, which is another option in Photoshop).
Hope this helps a bit ..